Sucralose -- Absorption and Accumulation

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According to the U.S. Food and Drug Administration, 11 to 27 percent of ingested sucralose is absorbed by the human body (FDA 1998). Research published by the manufacturer of sucralose (Roberts 2000) shows that when 8 healthy male adults where given sucralose (in 1 mg/kg amounts), between 10.4% and 30.6% of the sucralose was absorbed. In addition, 1.6% to 12.2% of the sucralose accumulates in the body. See Table 2 in Roberts (2000). No information is given as to whether it accumulates as sucralose or other chemicals

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References

FDA 1998. Food Additives Permitted for Direct Addition to Food for Human Consumption; Sucralose," 21 CFR Part 172, Docket No. 87F-0086, 1998. Federal Register: April 3, 1998 (Volume 63, Number 64, Page 16417-16433). http://vm.cfsan.fda.gov/~lrd/fr980403.html.

Roberts, A., A.G. Renwick, J. Sims, D.J. Snodin, 2000. "Sucralose Metabolism and Pharmacokinetics in Man," Food and Chemical Toxicology, Volume 38, Supplement 2, pages S31-S41, 2000.